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Mycoplasma bovis Added to Zactran Label

April 12, 2012
 
 

DULUTH, Ga. — Merial has announced that Zactran (gamithromycin), its rapid-response weapon in the battle against bovine respiratory disease (BRD) in high-risk cattle, is now approved for the treatment of Mycoplasma bovis.M. bovis is a significant pathogen in dairy calves associated with clinical cases of BRD, which costs the dairy industry nearly $30 million per year.
 
With this approval, prescription Zactran is labeled as a first-pull treatment for all major pathogens of BRD in beef and dairy heifers under 20 months of age, including Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and M.bovis. In addition, Zactran is labeled to control respiratory disease in beef and nonlactating dairy cattle at high risk of developing BRD associated with M. haemolytica and P. multocida.
 
Bruce Nosky, manager of Merial Large Animal Veterinary Services, says BRD is a complex disease that often involves a calf’s immune system, stressors, virus infection, and one or more bacterial pathogens. "It is not uncommon to have mixed bacterial infections resulting in BRD, which is why it’s so important to use a broad-spectrum antimicrobial," he says. "Veterinarians and producers need cattle to respond quickly to treatment, and they can be confident in Zactran. They can also be confident in the fact that the M. bovis post-approval claim was achieved by successfully completing FDA-approved studies conducted in feedyards, which allowed us to garner real-world product results."
 
In field studies conducted for the initial product approval, cattle treated with Zactran showed a rapid improvement in BRD clinical signs.More than three-quarters of the cattle with a fever had a significant decrease in temperature within 24 hours. And the majority of those cattle treated with Zactran remained healthy throughout the 10-day study.In additional field trials for BRD control, the majority of lightweight, long-haul and high-risk cattle that received Zactran on arrival to control BRD showed significantly less disease during the 10-day study compared to nontreated calves.
 
Zactran is a prescription product and is administered subcutaneously at a dose of 2 ml/110 lb.It is available in three ready-to-use sizes: 100, 250 and 500 ml. Every 250- and 500-ml bottle includes a durable bottle protector.
 
Producers can learn more about Zactran by contacting their veterinarian or visiting www.zactran.com.

RELATED TOPICS: Dairy, New Products

 

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